The major cannabinoid cannabichromene (CBC) has attracted much attention in recent years for its unique properties. Even though solid research into this cannabinoid is in its infancy, CBC is thought to be the second-most abundant phytocannabinoid we find in marijuana. It is also viewed as a key to understanding the complex nature of how whole-plant cannabis medication works, especially in how they work together to fight cancer, promote bone growth, and treat dozens of other ailments.
CBC forms as a result of the decarboxylation of its precursor, cannabichromene carboxylic acid (CBC-A), which causes the compound to lose a molecule of carbon dioxide (CO2) either by the natural release of enzymes by the plant over time or the compound being ignited by heat. Though we don't know much about CBC, we do know that it is a non-psychoactive compound that exhibits a range of therapeutic effects.
For instance, CBC has well-known antibacterial and anti-fungal properties. We can look back to 1981 when researchers from the University of Mississippi reported that after administering CBC to several different strains of bacteria and fungi the compound's they found that “antibacterial activity was strong, and anti-fungal activity was mild to moderate.”
CBC also offers mild relief from pain, swelling and inflammation, and particularly inflammation of the intestinal tract. In 2012 researchers from the University of Naples reported that CBC had shown to reduce hypermotility (diarrhea) without causing hypomotility (constipation) as many medications do now. Another interesting property of CBC is its role in treating acne, as it was shown in 2016 by a team of European researchers that CBC reduced both the effects of arachidonic acid and the production of sebum by sebaceous glands, which produce symptoms of acne.
However, the most exciting prospects of CBC may lie in its unique ability to help promote the growth and viability of developing brain cells (neurogenesis). A 2013 study at the Institute of Biomolecular Chemistry of the National Research Council (ICB-CNR) in Pozzuoli, Naples, Italy tested CBC and two other cannabinoids for their effect on adult neural stem progenitor cells (NSPCs) and found that “CBC has a positive effect on the viability of mouse NSPCs.” This is significant as nearly all other mind-altering substances inhibit brain cell growth.