To say Bill Maher is an outspoken supporter of cannabis legalization is like saying Ann Coulter kinda dislikes liberals.

Maher's scathing wit has helped reshape the conversation around cannabis for years. He's repeatedly called on President Obama to reform America's drug laws, and he's even dubbed Colorado the " Jackie Robinson of pot" for being the first U.S. state to legalize.

In honor of his 60th birthday, we've put together some of the best cannabis moments from Real Time with Bill Maher.

1. Skewering hypocritical politicians

Bill Maher joked about his pot use in this Feb. 20, 2015 episode by quipping: "When I was younger, I used to smoke pot. And by when I say 'when I was younger,' I mean just before the show."

The joke led to him laying into politicians like Jeb Bush who oppose legalization even though they smoked cannabis when they were younger:

"The problem I have is that this is the standard answer we get from all these guys nowadays. Some form of 'Hey, when I was young and stupid, I was young and stupid. It's no big deal.' Which is great. Except it's not a defence that's really available for most of the 700,000 Americans who get arrested every year. So if we're going to keep doing that, we should at least be honest with our kids. And tell them the truth about drug laws in this country: 'Kids, if you're going to experiment, make absolutely certain that beforehand, your parents are white and well connected.'"

In the same clip, he calls on Obama to legalize cannabis and offer amnesty to drug offenders:

2. Mocking hysterical rhetoric

On Oct. 9, 2015, former Rhode Island representative, and anti-pot crusader Patrick J. Kennedy - yes, of those Kennedys - sat down for a grilling that began with a rough start: "You said marijuana destroyed the brain and expedited psychosis," Maher noted in reference to remarks given to The Washington Post. "It sounds like you've been hanging around with Nancy Reagan in 1983."

Kennedy - like many legalization opponents in America and in Canada - defended his stance by saying legal weed would endanger children. But Maher quickly tore that argument apart:

"But you're reasoning is: adults shouldn't do things because kids might. Adults shouldn't have fire or drive cars under that reasoning too."

Check out the two sparring over science, health and public safety:

3. Offering free advice to Republicans

"Pot is the new gay marriage," Maher declared on May 31, 2013. And he suggested it was a social justice issue that the GOP would be wise to rally around:

"If Republicans were smart, they would steal marijuana legalization away from the Democrats as a freedom issue. Of course, they're not smart, so they won't. Because they're squares living in a Reefer Madness cartoon. A cartoon where millions of Americans are still trapped in a no man's land where a pot dispensary can sell you weed so long as you have a 'card' from a 'doctor' who certifies that you have a 'disease.' Which is just 'Don't Ask, Don't Tell' for pot smokers."

Later in the segment, he looked at the racial injustice behind the War on Drugs as a form of voter suppression:

4. The origins of Green Day

Not all of Maher's interviews focus on the heavy issues of legalization. He's also had some lighthearted chats with people in the culture such as Billie Joe Armstrong - frontman of Green Day - who confirmed rumors that the band's name is an allusion to cannabis: "Oh, it was absolutely about pot. We were trying to be the Cheech and Chong of punk rock for a while. And some of us still are the Cheech and Chong of punk rock... in a lot of ways."

Armstrong then discusses why he doesn't like being high around his kids (and it's not why you think):

5. Zach Galifianakis sparks controversy

The Hangover star stole the show on Oct. 29, 2010 when he upstaged a discussion of legalization in California by "pulling a Cypress Hill."

h/t The Guardian, UPROXX, Cleveland

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