If you've ever felt a little worse for wear after chasing a puff with a few beers, there's a reason for that. Mixing marijuana with alcohol has a different effect on the body and brain than consuming either intoxicant separately.

While liquor enhances the high of cannabis, cannabis can help offset some of the damage that a night of hard drinking can do on your liver. But drinking and toking at the same time isn't necessarily a good idea since marijuana can worsen the effects of alcohol poisoning. Here's why according to the physiology experts at the YouTube channel AsapSCIENCE.