Robin Williams once joked that marijuana is performance-enhancing, “the only way it's a performance-enhancing drug is if there's a big f---ing Hershey bar at the end of the run." Many cannabis consumers agree, because depending on the person, strain, and a number of other factors, people react to marijuana differently. Other cannabis consumers disagree with Robin Williams though, as it actually helps them perform better at certain tasks, activities or sports.

Many athletes consume cannabis because they agree that marijuana’s influence helps them unlock performance gains that bring them to a higher level. Elite triathlete Clifford Drusinsky leads training sessions fueled by marijuana edibles, "Marijuana relaxes me and allows me to go into a controlled, meditational place. When I get high, I train smarter and focus on form." THC attaches to cannabinoid receptors throughout our brains, triggering a system that reduces anxiety, which improves performance. Marijuana helps athletes recover as well because its anti-inflammatory properties relieve pain and soreness. Cannabis is also a performance-enhancer for less physical activities such as writing. Many successful writers and authors claim to consume cannabis to help them put drafts together. Author Ken Kesey (“One Flew Over the Cuckoo’s Nest”) consumed a number of drugs, including marijuana, to write “Sometimes a Great Notion”.