Cannabis has been consumed by many different cultures for thousands of years. Marijuana is one of the oldest known psychoactive drugs which has been used all across the world. In Ancient Egypt for example, cannabis was used as a pain-reliever and traces of it is found in the remains of a number of mummies. In Early America, the marijuana grown was cannabis sativa L, which contains less than 1% THC, not nearly enough for anyone to get high. There is also some evidence that indicates that cannabis was consumed during the Renaissance, a time of profound creativity and artistry.

During this time of creativity in Europe, Renaissance writer François Rabelais was writing about pantagruelion in his series of books, “The Life of Gargantua and of Pantagruel”. Pantagruelion is a plant often compared and even identified as cannabis for having similar qualities. Other than just writing about the plant, many people used cannabis for pain relief, which Rabelais said could ease gout pains, cure horses of colic, and treat burns. Rabelais also mentioned that pantagruelion and marijuana was also used as it is today, for smoking, “...his tongue in a stem of Pantagruelion, blew bubbles and gurgled.”